FlexoPlex™ - Live Life with Less Pain!

Effectively address the root causes of your joint pain without scary drugs!

You probably can't remember the first time your knees ached after your weekly basketball game... or when you began to find gardening physically agonizing instead of pleasurable...

Whether due to arthritis or just the wear and tear of daily living, your joint pain and tenderness has become a crippling problem instead of an occasional annoyance.

• Your joints are swollen, tender, and sore to touch.
• You avoid activities you used to love because they are simply too painful.
• You've experienced a decreased range of motion in your hands, hips, knees, and other joints.
• Your back, feet, and hands are stiff and sore.
• You find yourself longing for the days when your joints didn't hurt.

FlexoPlex™ Addresses All Aspects of Joint Pain

The specialized and powerful ingredients in FlexoPlex™ will deliver remarkable and lasting pain relief. Glucosamine, MSM and Chondroitin REBUILD and REPAIR worn and damaged joints. Essential fatty acids, including Omega 3 oil, LUBRICATE stiff joints, and natural COX-2 inhibitors SOOTHE sore joints. Some of the INCREDIBLE RESULTS you can expect from FlexoPlex™ include:

• An increased range of motion
• Joints that are more lubricated
• Better mobility
• Enhanced flexibility
• Less pain

FlexoPlex™ also promotes bone health, boosts the supply of blood and beneficial nutrients to tissues and cartilage, and encourages the synthesis of synovial fluid and the cartilage matrix. FlexoPlex™ will NOT interfere with the production of endorphins and enkephalins, powerful pain killers produced by the body.

FlexoPlex™ Success Stories!

I was always puttering in the garden but started to have trouble doing the simple things like weeding and pruning. My hands and knees just couldn't take the pain. I saw an ad for FlexoPlex™ and decided to give it a try. I was surprised at the difference one week made. My hands were not as stiff and my knees did not ache any more. FlexoPlex™ has really made a huge difference and gotten me back outside where I belong - Joni D., Miami, Fl.

I played competitive football in high school and college and sustained a few injuries during my playing time. I just turned 35 and really have terrible pain in my ankles and knees.I tried just taking NSAIDS but they really bothered my stomach so I decided to try FlexoPlex™. I was pumped by the way it worked. I could actually move easier and even began a light exercise routine again. FlexoPlex™ has really had a positive impact on my life - Hank C., Salem, Ma.

I just turned 55 years old. I used to take Celebrex for my arthritis but was afraid of all the adverse effects they were reporting. I have been taking FlexoPlex for a couple of months and have really noticed the difference in my range of motion and my pain has gone away. On top of my arthritis, I was having a hard time sleeping. Since I had so much success with FlexoPlex™ I decided to give Restocore™ a try. I am 2 for 2! I have been able to get to sleep peacefully and stay asleep all night long. Your product line is wonderful! - PattiAnn K., Grand Rapids, Michigan

I have to tell you I really love how Flexoplex™ makes me feel. I am more active now than I was when I was in my 30s. I play golf 3 times a week and hike every weekend. I had such terrible knee pain that my life was put on hold. Flexoplex™ gave me back my active lifestyle! - Jesse D., Sonoma, Ca

Clinical Studies

Glucosamine Sulfate

Taking glucosamine sulfate orally significantly improves symptoms of pain and functionality in patients with osteoarthritis of the knee in studies lasting up to 3 years. Numerous clinical studies show how Glucosamine benefits those suffering from aching joints. Works by repairing the smooth rubber-like padding (cartilage) covering the ends of bones.

1. McAlindon TE, LaValley MP, Gulin JP, Felson DT. Glucosamine and Chondroitin for Treatment of Osteoarthritis A Systematic Quality Assessment and Meta-analysis. JAMA 2000;283:1469-75.
2. Drovanti A, Bignamini AA, Rovati AA. Therapeutic activity of oral glucosamine sulfate in osteoarthrosis: a placebo-controlled, double-blind investigation. Clin Ther 1980;3:260-72.
3. da Camara CC, Dowless GV. Glucosamine sulfate for osteoarthritis. Ann Pharmacother 1998;32:580-7
4. Lopes Vaz AL. Double-blind, clinical evaluation of the relative efficacy of ibuprofen and glucosamine sulphate in the management of osteoarthrosis of the knee in out-patients. Curr Med Res Opin 1982;8:145-9.
5. Pujalte JM, Llavore EP, Ylescupidez FR. Double-blind clinical evaluation of oral glucosamine sulphate in the basic treatment of osteoarthrosis. Curr Med Res Opin 1980;7:110-4.
6. Qiu GX, Gao SN, Giacovelli G, et al. Efficacy and safety of glucosamine sulfate versus ibuprofen in patients with knee osteoarthritis. Arzneimittelforschung 1998;48:469-74.
7. Forster K, Schmid K, Rovati L, et al. Longer-term treatment of mild-to-moderate osteoarthritis of the knee with glucosamine sulfate- a randomized controlled, double-blind clinical study. Eur J Clin Pharmacol 1996;50:542.
8. Reginster JY, Deroisy R, Rovati LC, et al. Long-term effects of glucosamine sulfate on osteoarthritis progression: a randomized, placebo-controlled trial. Lancet 2001;357:251-6.
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9. Pavelka K, Gatterova J, Olejarova M, et al. Glucosamine sulfate use and delay of progression of knee osteoarthritis: A 3-year, randomized, placebo-controlled, double-blind study. Arch Intern Med 2002;162:2113-23.
10. Richy F, Bruyere O, Ethgen O, et al. Structural and symptomatic efficacy of glucosamine and chondroitin in knee osteoarthritis: a comprehensive meta-analysis. Arch Intern Med 2003;163:1514-22.
11. Braham R, Dawson B, Goodman C. The effect of glucosamine supplementation on people experiencing regular knee pain. Br J Sports Med 2003;37:45-9.
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12. Bruyere O, Pavelka K, Rovati LC, et al. Glucosamine sulfate reduces osteoarthritis progression in postmenopausal women with knee osteoarthritis: evidence from two 3-year studies. Menopause 2004;11:138-43.
13. Towheed TE, Anastassiades TP, Shea B, et al. Glucosamine therapy for treating osteoarthritis. Cochrane Database Syst Rev 2001;1:CD002946.
14. Towheed TE, Maxwell L, Anastassiades TP, et al. Glucosamine therapy for treating osteoarthritis. Cochrane Database Syst Rev 2005;(2):CD002946.

Glucosamine sulfate decreases pain scores by about 28% to 41% and improve functionality scores by 21% to 46%

1. Poolsup N, Suthisisang C, Channark P, Kittikulsuth W. Glucosamine long-term treatment and the progression of knee osteoarthritis: systematic review of randomized controlled trials. Ann Pharmacother 2005;39:1080-7.
2. Towheed TE, Maxwell L, Anastassiades TP, et al. Glucosamine therapy for treating osteoarthritis. Cochrane Database Syst Rev 2005;(2):CD002946.

MSM (Methylsulfonylmethane)

Provides reduction in symptoms of joint and musculoskeletal wear and tear.

1. Usha PR, Naidu MUR. Randomised, double-blind, parallel, placebo-controlled study of oral glucosamine, methylsulfonylmethane and their combinations. Clin Drug Invest 2004;24:353-63.
2. Kim LS, Axelrod LJ, Howard P, et al. Efficacy of methylsulfonylmethane (MSM) in osteoarthritis pain of the knee: a pilot clinical trial. Osteoarthritis Cartilage 2006;14:286-94.

Hyaluronic Acid

Prevents the breakdown of natural cushioning barriers in joint

1. Petrella RJ, DiSilvestro MD, Hildebrand C. Effects of hyaluronate sodium on pain and physical functioning in osteoarthritis of the knee: a randomized, double-blind, placebo-controlled clinical trial. Arch Intern Med 2002;162:292-8.

Omega 3 Essential Fatty Acids (Fish Body Oil)

Lubricates joints and reduces inflammation due to exertion.

1. van der Tempel H, Tulleken JE, Limburg PC, et al. Effects of fish oil supplementation in rheumatoid arthritis. Ann Rheum Dis 1990;49:76-80.
2. Fortin PR, Lew RA, Liang MH, et al. Validation of a meta-analysis: the effects of fish oil in rheumatoid arthritis. J Clin Epidemiol 1995;48:1379-90.

Rutin, Bromelain, Trypsin

Similar to NSAIDs in relieving pain and improving knee function

1. Klein G, Kullich W. Short-term treatment of painful osteoarthritis of the knee with oral enzymes. Clin Drug Invest 2000;19:15-23.

Boron (as aspartate)

Decrease symptoms of osteoarthritis

1. Newnham RE. Essentiality of boron for healthy bones and joints. Environ Health Perspect 1994;102:83-5.